| Classification Oral Contraceptives Indications OC. Dosage 1 tab daily from the 5th day of menstruation. Contraindications Thrombophlebitis, thromboembolic disorders or past history of these conditions; cerebrovascular disease or coronary artery disease; undiagnosed abnormal genital bleeding, known or suspected breast carcinoma, estrogen-dependent neoplasia or history of these conditions; liver tumor; pregnancy. Precautions Smoking, age; history of mental depression;liver impairment, cardiac or renal dysfunction, hypertension, uterine fibroids, diabetes, asthma, epilepsy, migraine; lactation. Adverse Reactions Nausea, vomiting, abdominal cramps, spotting, breakthrough bleeding, changes in menstrual flow, dysmenorrhea, amenorrhea during & after treatment, migraine & mental depression. Interactions Effcacy may be reduced by certain antibiotics, phenytoin, carbamazeping, barbiturates, rifampicin. |